Genotoxic Effects in Cultured Mammalian Cells Produced by Low pH Treatment. Conditions and (13) Kirkland D., Aardema M., Henderson L., och Müller L. (2005). (2002). Fixation of Testes and Eyes Using a Modified.
av GB Ehret · Citerat av 270 — Müller, Gabriele (författare): Müller-Nurasyid, Martina (författare): Mach, François Wong, Tien Y. (författare): Singapore Natl Eye Ctr, Singapore Eye Res Inst, enriched for cis-regulatory elements, particularly in vascular endothelial cells,
Müller cells express numerous voltage-gated channels and neurotransmitter receptors, which recognize a variety of neuronal signals and trigger cell depolarization and intracellular Ca2+ waves. Müller cells are the predominant glial cell type in the retina of vertebrates. They play a wide variety of roles in both the developing and the mature retina that have been widely reported in the literature. Müller cells constitute the dominant glial cell type in the retina. They are the only cells spanning the entire thickness of the tissue, thus connecting the inner with the outer retinal surface.
To dissect the role of vascular endothelial growth factor receptor-2 (VEGFR2) in Müller cells and its effect on neuroprotection in diabetic retinopathy (DR), we disrupted VEGFR2 in mouse Müller glia and determined its effect on Müller cell survival, neuronal integrity, and trophic factor production in diabetic retinas. Diabetes was induced with streptozotocin. Retinal function was measured Müller cells are the predominant glial cell type in the retina of vertebrates. They play a wide variety of roles in both the developing and the mature retina that have been widely reported in the literature. Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate transport, Müller cells control the composition of the extracellular space fluid.
Exp Eye Res. 2016 Feb 12;145:297-316. Müller cells are the most abundant type of glial cells found in the vertebrate retina, and perform diverse functions that support the activity of retinal neurons.
av C Lindqvist · 2014 — Polymer solar cells are a promising alternative to more traditional silicon solar cells. This is mainly Camilla Lindqvist, Ergang Wang, Mats R. Andersson, Christian Müller. Macromolecular Red line is a guide to the eye. Reese et al. have
While their cell bodies are located in the inner nuclear layer of the retina, they span across the entire retina. Abstract. Müller glial cells span the entire thickness of the tissue, and ensheath all retinal neurons, in vertebrate retinae of all species.
En tredje typ av ljuskänsliga cellen, den ljuskänsliga gangliecell , är viktigt för Flera viktiga funktioner i visuell perception kan spåras till retinal att det finns ett tunt lager av Müller-cellfotplattor mellan detta lager och det inre
Müller cells from both species were Müller cells in fish have the ability to revert back to a stem cell form and regenerate damaged eye tissue. Humans and mice also have Müller cells, but internal signals prevent the cell type from carrying out regenerative duties. Muller cells of stretch-activated ion channels that are permeable to monovalent and divalent cations. MATERIALS AND METHODS Cultures of retinal glial cells were prepared as de- scribed previously (Puro et al., 1990; Puro and Mano, 1991). In brief, postmortem eyes from donors aged 62 to 81 years were supplied within 24 h of death by the 2011-12-07 · 661W cells (a gift from Drs Zhongshu Tang and Xuri Li, National Eye Institute, Bethesda, MD), a photoreceptor-derived cell line, were plated in 96-well plates at a density of 1 × 10 4 cells/well.
Conditions and (13) Kirkland D., Aardema M., Henderson L., och Müller L. (2005).
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PhD in Animal Physiology specialized within the field of toxicology, cell biology, e.g. cytotoxicity, gene mutations, skin and eye irritation, and skin corrosion. -Löfdahl A, Rydell-Törmänen K, Müller C, Martina Holst C, Thiman L, Ekström G, More on authors: Müller & Henle. The spine is coated with an extremely toxic mucus produced by the cells of the skin and inflicts very painful wounds (Ref. En tredje typ av ljuskänsliga cellen, den ljuskänsliga gangliecell , är viktigt för Flera viktiga funktioner i visuell perception kan spåras till retinal att det finns ett tunt lager av Müller-cellfotplattor mellan detta lager och det inre SANTESSON L.: Characteristics of epithelial mouse tumour cells in vitro and tumour GOTTFREDSEN E.: Eye and nerve symptoms in connection with crnnial MOBERGER G., MULLER W. und BAHR G. F.: Das Vorkornmcn und die av BH Skogman · 2008 · Citerat av 1 — with consequences such as eye-closing problems, excessive tear secretion, pronunciation IFN-γ secreting cells in CSF was found to be more prominent in children with NB than in controls.
Dissecting the mechanisms that zebrafish use could lead to new therapeutic targets to treat retinal diseases. Patton and colleagues have discovered a mechanism by which decreased GABA levels are sensed by Müller glia to initiate a regenerative response. Several endogenous populations of cells localized to the eye have been shown to be capable of replacing some or all retinal cell types in various species; 1) an endogenous population of progenitor cells in the periphery of the eye referred to as the ciliary marginal zone (CMZ), 2) the retinal pigmented epithelium, 3) non-pigmented cells adjacent to peripheral retina, 4) NG2 + glial progenitors
23 Mar 2020 Schepens Eye Research Institute of Massachusetts Eye and Ear, Müller cells ( MCs) are the major type of glial cells in the retina [1].
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av L Cordain · 2002 · Citerat av 230 — eye. Cass (1966, 1973) has likewise re- ported low incidence rates of myopia in. Eskimo adults when knockout cells lacking the IGF receptor. (Valentinis et al. 1995). Juul A, Scheike T, Nielsen CT, Krabbe S, Muller. J & Skakkebaek NE
Astrocytes are not glial cells of the retinal neuroepithelium but enter the developing retina from the 3. Microglial Müller cells in the parafoveal region, unlike the central inverted plug, display a remarkable ‘z-shaped’ anatomical configuration, which has long being known since Ramon y Cajal. 6 The horizontal part of the z-shaped Müller cells contributes to the Henle's fibre layer (HFL) comprised of bundles of cone and rod photoreceptor axons terminating in the pedicles and spherules, respectively, that form synapses in the retinal outer plexiform layer (OPL). Muller cells are glia found in the eyes of all mammals. A few will be available to trace for triple points in Eyewire for two days only: All Hallows’ Eve and Dia de los Muertos (Oct 31-Nov 2). To trace them you must pass Level 2 in Eyewire! Cells will be online until Nov 2 or until they’re completed.
Human species D adenovirus hexon capsid protein mediates cell entry through a direct Variant and Human Adenovirus Type 37-Viruses That Cause Highly Contagious Eye Infections Persson, B David; Müller, Steffen; Reiter, Dirk M; et al.
They play a wide variety of roles in both the developing and the mature retina that have been widely reported in the literature. Müller cells constitute the dominant glial cell type in the retina. They are the only cells spanning the entire thickness of the tissue, thus connecting the inner with the outer retinal surface. These tubular cells widen towards the inner retinal surface and terminate in funnel-like endfeet. However, this loss of Müller cells has been observed in every eye that has been donated to the MacTel Project. While this is a small number, it provides strong evidence that Müller glia loss is part of the disease.
These findings resembled the appearances found in proliferating Müller cells in the human eye. The ultrastructural differences noted in the cultured Müller cells suggest that the cultured cells are Müller cells and microglial injury responses in the retina have been ascribed both beneficial and deleterious features [ 8 – 10 ], and the "Janus-faced" nature of these responses may be secondary to the complex system of communications between microglia and macroglia. Within the eye, a type of cell called the Müller cell, which is found in the retina, is known to act as a stem cell in some species, such as the zebra fish. It has been suggested that this cell may also be able to act as a stem cell in humans, in which case it may provide another source of retinal cells for repair of the retina.